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Original Article
Egyptian Journal of Basic and Clinical Pharmacology
Vol. 7 (2017), Issue 1, pp. 57-60
doi:10.11131/2017/101365

Antioxidant Activity of Quercetin 3-O-alpha-L-Arabinopyranoside Isolated from Hibiscus Vitifolius (Linn.) in Mercury Chloride Induced Toxicity

Sasikumar Dhanarasu1, Mathi Selvam1, and Nouh M. H. Aljarari2

1Department of Biochemistry, College of Medicine, University of Ha’il, Kingdom of Saudi Arabia

2Department of Pharmacology, Medicine Faculty, Benghazi University, P.O. Box: 7806, Benghazi, Libya


Copyright © 2017 Sasikumar Dhanarasu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The fresh flowers of Hibiscus vitifolius Linn. were screened to determine antioxident activity. A methanol extract of flower was prepared and partitioned sequentially with petrol, ether and ethyl acetate. The active compounds were identified by UV, 1H NMR (Proton Nuclear Magnetic Resonance) and 13C NMR (Carbon-13 Nuclear Magnetic Resonance) as quercetin and quercetin 3-0-arabinopyranoside. The antioxident activity was also studied in mercury chloride (HgCl2) toxicity through biochemical parameters such as SOD, CAT, GSH, GPX, AST, LPO, vitamin C, vitamin E and urea. Quercetin 3-0-arabinopyranoside treated rats showed decrease in lipid peroxidation. Statistically significant increased in enzymes compared to HgCl2 induced group was observed. Which indicates that quercetin 3-0-arabinopyranoside isolated from the flowers of Hibiscus vitifolius act as a potent antioxidant.

Original Article
Egyptian Journal of Basic and Clinical Pharmacology
Vol. 7 (2017), Issue 1, pp. 57-60
doi:10.11131/2017/101365

Antioxidant Activity of Quercetin 3-O-alpha-L-Arabinopyranoside Isolated from Hibiscus Vitifolius (Linn.) in Mercury Chloride Induced Toxicity

Sasikumar Dhanarasu1, Mathi Selvam1, and Nouh M. H. Aljarari2

1Department of Biochemistry, College of Medicine, University of Ha’il, Kingdom of Saudi Arabia

2Department of Pharmacology, Medicine Faculty, Benghazi University, P.O. Box: 7806, Benghazi, Libya


Copyright © 2017 Sasikumar Dhanarasu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The fresh flowers of Hibiscus vitifolius Linn. were screened to determine antioxident activity. A methanol extract of flower was prepared and partitioned sequentially with petrol, ether and ethyl acetate. The active compounds were identified by UV, 1H NMR (Proton Nuclear Magnetic Resonance) and 13C NMR (Carbon-13 Nuclear Magnetic Resonance) as quercetin and quercetin 3-0-arabinopyranoside. The antioxident activity was also studied in mercury chloride (HgCl2) toxicity through biochemical parameters such as SOD, CAT, GSH, GPX, AST, LPO, vitamin C, vitamin E and urea. Quercetin 3-0-arabinopyranoside treated rats showed decrease in lipid peroxidation. Statistically significant increased in enzymes compared to HgCl2 induced group was observed. Which indicates that quercetin 3-0-arabinopyranoside isolated from the flowers of Hibiscus vitifolius act as a potent antioxidant.

Original Article
Egyptian Journal of Basic and Clinical Pharmacology
Vol. 7 (2017), Issue 1, pp. 57-60
doi:10.11131/2017/101365

Antioxidant Activity of Quercetin 3-O-alpha-L-Arabinopyranoside Isolated from Hibiscus Vitifolius (Linn.) in Mercury Chloride Induced Toxicity

Sasikumar Dhanarasu1, Mathi Selvam1, and Nouh M. H. Aljarari2

1Department of Biochemistry, College of Medicine, University of Ha’il, Kingdom of Saudi Arabia

2Department of Pharmacology, Medicine Faculty, Benghazi University, P.O. Box: 7806, Benghazi, Libya


Copyright © 2017 Sasikumar Dhanarasu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Sasikumar Dhanarasu, Mathi Selvam, and Nouh M. H. Aljarari, “Antioxidant Activity of Quercetin 3-O-alpha-L-Arabinopyranoside Isolated from Hibiscus Vitifolius (Linn.) in Mercury Chloride Induced Toxicity,” Egyptian Journal of Basic and Clinical Pharmacology, Vol. 7, Issue 1, pp. 57-60, 2017. doi:10.11131/2017/101365