Table 3: AUC, sensitivity, specificity, positive and negative predictive values for ICDAS and CarieScan Pro at the D3 diagnostic threshold (dentine caries).


Method AUC (Standard error) 95% CI SE (%) SP (%) PPV(%) NPV (%) Cut-off

ICDAS 0.93 (0.03) 0.87-0.96 72.0 96.6 81.8 94.3 2/3
CarieScan Pro 0.84 (0.05) 0.77-0.90 68.0 90.8 60.7 93.1 90/91

AUC = Area under the curve; CI = Confidence interval; SE = Sensitivity; SP = Specificity PPV = positive predictive value; NPV = negative predictive value