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Cancer Science and Pediatrics 2019: Limb-sparing surgery with vascular reconstruction in lower extremity soft tissue sarcoma: promising results - Khalid Mowafy - Mansoura University, Egypt | Abstract

Pediatric Oncology: Open Access

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Cancer Science & Pediatrics 2019: Limb-sparing surgery with vascular reconstruction in lower extremity soft tissue sarcoma: promising results - Khalid Mowafy - Mansoura University, Egypt

Author(s): Khalid Mowafy

There is uncertainty in the literature as to whether major vessel involvement in extremity soft tissue sarcomas constitutes an indication for amputation. This prospective study includes fifteen patients with lower extremity soft tissue sarcomas who underwent major vessel resection and reconstruction in the context of limb preservation for soft tissue sarcoma. Limb salvage surgical procedure includes all the surgical strategies designed to perform removal of a malignant tumor and reconstruction of the limb with an appropriate oncologic, functional, and cosmetic result. In the latest past, most sarcomas had been handled by way of amputation.

Tumor recurrence, metastasis, and a generally dismal analysis were a powerful deterrent to development in remedy. Limb salvage surgical operation has all but replaced amputation as the treatment of choice for sarcomas of the extremities. This dramatic change came about as the result of vital developments: powerful chemotherapy 35 and precision imaging strategies. 69 In the early 1970’s, new anti—neoplastic pills inclusive of Adriamycin and methotrexate have been introduced, and awesome improvements in the prognosis for some sarcomas were seen.2’three In the past due 1970’s, the development of CT and MRI allowed medical doctors to more exactly outline the anatomic quantity of the tumor, making it less difficult to eliminate the sarcoma without resorting to amputation. Today, up to 85% of sarcomas inside the extremities are treated with limb salvage surgery.

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