Abstract
Author(s): Leonardo Milella
The Blood purification technique is very quickly taking place in septic shock and sepsis treatment. The application of these techniques to neonates and paediatric patients is still very difficult for many reasons: the absence of a dedicated device, the difficult stability of cardio-circulatory function, the difficult management of fluid volumes is not complete in organ development, and not adequate and specific inflammatory response. The increased incidence of complications related to a prolonged duration of blood purification treatment has to be overtaken. Different blood purification techniques as CRRT-CVVH-D, CVVHD, and plasmapheresis are used in sepsis and MOF treatment but the timing of cytokines removal is prolonged and the recirculation of the not removed products delays the cut off of inflammatory response.
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