Figure 4: The c-MYC promoter. The figure represents an approximate 3 kilobase segment surrounding the 5' end of the human c-MYC gene. Red arrows indicate the four MYC promoters (P0 to P3), as defined by transcriptional start sites (the P0 promoter has multiple transcriptional start sites). MYC exons one and two are represented as gray boxes; “+1” indicates the translation start site for the canonical `p64' MYC protein. Nuclease sensitive regions are indicated as red circles. The relative location of the FUSE and NHE III1 elements are presented, below which appears the nucleotide sequence of each element.