The Open Access Journal of Science and Technology

Abstract

Prevalence of Urinary TractInfection,Microbial Aetiology,and Antibiotic Sensitivity Pattern among Antenatal Women Presenting with Lower Abdominal Pains at Kenyatta National Hospital, Nairobi,Kenya

Author(s): Willy Fred Nabbugodi,J.Wanyoike Gichuhi,and N.W.Mugo

Objective.Todeterminetheprevalenceofurinarytractinfectionasacauseoflowerabdominalpainsamongantenatal womenanditsaetiologicalmicroorganismanddefinethesensitivitypatterntocommonlyusedantibiotics.StudyDesign.Across sectional study. Setting. Kenyatta National Hospital, Nairobi, Kenya. Subjects. One hundred and fifty antenatal women. Main Outcome Measures. Overall the prevalence of urinary tract infection, its aetiological causes, and antibiotic sensitivity pattern. Results.TheprevalenceofUTIamongantenatalwomenpresentingwithlowerabdominalpainsinKenyattaNationalHospitalwas foundtobe26.7%.Ofthe40womenwithpositivecultureurine,31(C77.8%)werealsopositiveondipstickand27(67.5%)were positiveonurinemicroscopy.Thereissignificantcorrelationbetweenurinedipsticktesting,urinemicroscopy,andpositiveurine cultureinUTI.DipsticktestandurinemicroscopytesthadhighsensitivityandspecificityinscreeningforUTI.Thepredominant bacterialpathogenswereEscherichiacoliat40%followedbyStaphylococcusspp.at25%andKlebsiellaspp.at10%.Therewere alsoEnterococcus,Enterobacter,andCitrobacterspecies.Theisolatedgram-negativebacteriawere100%sensitivetomeropenem, imipenem, augmentin, ceftazidime, and levofloxacin and about 81% to cefuroxime. The bacteria showed significant resistance togentamycinand ampicillinof upto80%. The isolatedgram-positivebacteriawere100% sensitivetoaugmentin,cefuroxime, ceftriaxone,ceftazidime,meropenem,andimipenembutshowedsignificantresistancetolevofloxacin,gentamycin,nitrofurantoin, andampicillinofbetween20%and80%.

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